AXL INHIBITION IN TREATMENT-RESISTANT METASTATIC ADENOID CYSTIC CARCINOMA




Long-term experimental evolution reveals purifying selection on piRNA-mediated control of transposable element expression

Abstract Background Shorts Transposable elements (TEs) are an almost universal constituent of eukaryotic genomes.In animals, Piwi-interacting small RNAs (piRNAs) and repressive chromatin often play crucial roles in preventing TE transcription and thus restricting TE activity.Nevertheless, TE content varies widely across eukaryotes and the dynamics

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